This post was from a user who has deleted their account.
My most epic loot drop was, in my opinion, in Zul'Gurub when I got the shield from Hakkar.
When i was farming for barons mount for like weeks straight.. then one night it dropped (i was so happy because my day had been going bad so far) and i was so happy, i started spamming Trade chat with "HAHAH I GOTZ MAH EPIC LEWT MOUNT BEAT THAT"and the rest of the day was people spamming me :D
The most epic item for me was the Headless Horseman mount. Nice to be able to use it in Azeroth, Outlands, and Northrend.
My most epic loot was more of a funny one. When I had been leveling I went to Gnomeregan to get the dagger off of Viscous, the elemental. A friend ran me through it at least 20 times, and that dagger never dropped, i had about 13 of those boots and 7 aquacanes. When I had finally reached 70 a friend asked me to run him, he was going for those boots that had dropped for me so many times. So we get to Viscous and I run up and kill him. We loot him, and low and behold, the dagger I had run so many times for drops. My friend proceeds to tell me, "Wow man haha, remember how many times you ran for this thing, why don't you take it, you can use it if you ever go daggers!" At this point I just looked at him, looted the dagger and immediately destroyed it out of spite, I signed off and didn't play Warcraft for a week, though that was more because I had other things to do. The drop was epic in it's own way, now that I look back on it, it's pretty funny.
I'd say my most epic loot would be World of Warcraft itself. Before i got it, i used to play on my sisters account (a lvl 10 paladin, woot) but she wouldnt let me play alot...Ah, the good old days.