For me it would have to be either the firefly after days of farming the little guy, or maybe the good ol' happy fun rock. Ah what the ogres will play with. Of course we've seen how they dance so it shouldn't surprise me.
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My epic loot was probably from back in the day when lich was just a wee little tauren. There I was leveling about and all the sudden there was this moon festival thing! So I took this random port to Moonglade, and there was this beautiful zone filled with non-hostile NPCs! Being the new person I was, I did every single quest I could for it, hoping I'd get something extremely nice. After a couple days of working, I'd finally accumulated enough coins to buy something nice, and this is what I bought: http://www.cuckhead.com/?item=21538#comments, the coolest damned dress in the entire game. At level 40, I spent many an hour begging like a fool in that dress, dancing for gold. Nowadays I'm not a begger, but I very often pull that dress out and wear it with my Stranglestaff and my X-52 Rocket Helmet.
My most epic loot was Dragon's call. I had been running ST for months pre-BC and when it dropped I went straight to the front doorstep of Org to duel everyone I could (cuz that was what the COOL kids did). I still have that sword, just because it looks pretty awesome and I love bringing it out every once in a while to have my whelps come out to everyone's surprise.
The Stoppable Force!Lolled to tears!
Weeks and weeks of missing it by seconds, people disconnecting during boss fights, rogues getting stuck outside doors, but finally we made it. Knowing that it meant so much to me everyone passed on the roll. When I finally got my Amani War Bear I literally cried. The first in what is now a small collection of cherished bears.
I would have to say that the most epic drop i have ever gotten was the very first epic I ever equipped. It was a Hide of the Wild that I spent many hours farming larval acids for. Nothing in the game felt better than my first.
Well, I know most people don't think this is epic, but I am really enjoying the recipes that are dropping in Wrath. You know, after the battle is over, there is nothing like curling up with some Bash Ale and a couple of Tasty Cupcakes. Gear will come and go, but tasty treats stay on the hips forever.
I think I have to say, my most epic loot ever was the disgusting oozling. I remember first reading about it on the beta realm patch notes, so I started farming for it the second the servers came up after the patch. It took me a solid week of non-stop farming and hundreds of ooze covered bags to finally get the pet.
The most epic drop I've ever gotten, involved a 2 week farming session in Zangarmarsh for a firefly pet, and just before I was about to give up on it, and go to the evenings raid I got aggro of one last one before I mounted up, and it DROPED! I was amazed, and shocked, however at the same time I was envious because I was not farming it for myself, even though I really wanted one, I was actually farming it for my Fiancee because she adores the little critter, so I was very, how you say, proud of myself for actually seeing it through and getting one for her, and she loves it, she's always got it out, well did atleast, I bought us collectors edition so we use Frosty now, but that firefly was my most epic drop ever, the first time I was ever able to prove to myself I could farm a really rare item.
My most epic thing in wow was taking down cthun (when it was something to brag about) most fun ive had progressing with my guild watching the warriors intercept into the lazer and die or jump behinde him and die pure comedy.
The most epic thing to me was when i did my frist dungeon, which was the library in Scarlet Monastery. we finally got to the end and defeated arcanist doan and the hypnotic blade droped. http://www.cuckhead.com/?item=7714i still have it just since it reminds me of my first dungeon completed.